Musashi 1/2 (AA 66-150) 抗体
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北京 101111
Quick Overview for Musashi 1/2 (AA 66-150) 抗体 (ABIN1387744)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 66-150
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Musashi 1
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Musashi 1/2
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背景
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Synonyms: Msi 1, Msi1, Msi-1, MSI1H_HUMAN, Musashi homolog 1, Musashi-1, Musashi1, Musashi 1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1, Msi 2, Msi2, Msi-2, MSI2H_HUMAN, Musashi homolog 2, Musashi-2, Musashi2, Musashi 2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2.
Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
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基因ID
- 4440, 124540
抗原
-
