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SNCA 抗体 (nTyr39)

SNCA 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387711
发货至: 中国
  • 抗原 See all SNCA 抗体
    SNCA (Synuclein, alpha (SNCA))
    抗原表位
    • 73
    • 31
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    • 23
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    • 5
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    nTyr39
    适用
    • 291
    • 198
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    • 14
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    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
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    人, 大鼠, 小鼠
    宿主
    • 237
    • 97
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 222
    • 120
    多克隆
    标记
    • 143
    • 25
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    • 11
    • 9
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    This SNCA antibody is un-conjugated
    应用范围
    • 237
    • 165
    • 110
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    • 68
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic nitrylpeptide derived from human Alpha-synuclein around nitration site of Tyr39
    亚型
    IgG
    Top Product
    Discover our top product SNCA Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-Synuclein (SNCA 产品)
    别名
    snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
    背景

    Synonyms: SYUA_HUMAN, nitrated Alpha-synuclein nitrated-Tyr39, nitrated Alpha-synuclein nitro-Tyr39, Alpha-synuclein nitro-Tyr39, Alpha-synuclein nitro Tyr39, nitrated Alpha synuclein, nitrated Alpha-Synuclein, Alpha synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid , precursor of, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease familial 1, PD 1, PD1, SNCA, Snca synuclein, alpha non A4 component of amyloid precursor, Synuclein alpha, Synuclein, alpha non A4 component of amyloid precursor.

    Background: The synuclein family members, including Alpha-synuclein (also designated NACP for non-Beta-Amyloid component) and Beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. Alpha-synuclein is localized to neuronal cell bodies and synapses. Alpha-synuclein was first identified as a component of Alzheimer?s disease amyloid plaques. Abnormal platelet function in Alzheimer?s disease has been demonstrated. During megakaryocytic differentiation Alpha-synuclein has been found to be upregulated, while Beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of Alpha-synuclein has been found in patients with early onset Parkinson?s disease.

    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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