PHF21A 抗体 (AA 351-450)
Quick Overview for PHF21A 抗体 (AA 351-450) (ABIN1387678)
抗原
See all PHF21A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-450
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PHF21A
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PHF21A (PHD Finger Protein 21A (PHF21A))
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别名
- BHC80/PHF21A
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背景
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Synonyms: BHC80a, BM-006, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35/HDAC2 complex 80 kDa, KIAA1696, PF21A_HUMAN, PHD finger protein 21A, PHF21A.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
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基因ID
- 51317
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途径
- Feeding Behaviour
抗原
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