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SYT11 抗体 (AA 51-100)

This anti-SYT11 antibody is a 兔 多克隆 antibody detecting SYT11 in ELISA, IF (cc), IF (p), ICC, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN1387635
发货至: 中国

Quick Overview for SYT11 抗体 (AA 51-100) (ABIN1387635)

抗原

See all SYT11 抗体
SYT11 (Synaptotagmin XI (SYT11))

适用

  • 35
  • 11
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  • 1
  • 1

宿主

  • 34
  • 2

克隆类型

  • 34
  • 2
多克隆

标记

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  • 1
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  • 1
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  • 1
  • 1
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This SYT11 antibody is un-conjugated

应用范围

  • 15
  • 12
  • 12
  • 11
  • 4
  • 2
  • 2
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-100

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Synaptotagmin XI

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    SYT11 (Synaptotagmin XI (SYT11))

    别名

    Synaptotagmin 11

    背景

    Synonyms: Synaptotagmin 11, Synaptotagmin 12, Synaptotagmin XI, Synaptotagmin-11, synaptotagmin XII, synaptotagmin-XII, Synaptotagmin11, Synaptotagmin12, Synaptotagmin-11, Synaptotagmin-12, SynaptotagminXI, SYT 11, SYT 12, SYT-11, SYT-12, Syt XI, Syt11, SYT11_HUMAN, SYT12, SytXI, DKFZp781D015, KIAA0080, MGC10881, MGC17226.

    Background: Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson?s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson?s disease.

    基因ID

    23208
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