DAB1 抗体 (pTyr198)
Quick Overview for DAB1 抗体 (pTyr198) (ABIN1387578)
抗原
See all DAB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr198
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr198 [V(p-Y)QY]
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亚型
- IgG
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anti-Disabled Homolog 1 (Drosophila) (DAB1) (pTyr232) antibody
DAB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 400-555) antibodyDAB1 适用: 小鼠 WB, ELISA, IHC, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 400-555) antibodyDAB1 适用: 小鼠 WB, ELISA, IHC, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (pTyr232) antibodyDAB1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (Ser296) antibodyDAB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 1-185) antibodyDAB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 187-236) antibodyDAB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 1-553) antibodyDAB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (C-Term) antibodyDAB1 适用: 人, 大鼠, 小鼠, Pig, 猴, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 1 (Drosophila) (DAB1) (AA 42-168) antibodyDAB1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
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别名
- Dab1
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背景
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Synonyms: Dab1 phospho Y198, Dab1 Tyr198 , Dab 1, Dab1, Dab-1, DAB1_HUMAN, Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari.
Background: Dab1, a homolog of the Drosophila Disabled protein, is an adaptor protein involved in neural development. This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family. Dab1 has been shown to interact with the SH2 domains of Src, Fyn and Abl (1). Mutations in Dab1 result in widespread abnormalities in the brain, similar to those seen in Reelin mutants (2). Reelin is a secreted protein thought to play a role in directing migrating neurons (3). Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4). Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, and it is thought to be a negative regulator of growth (5).
抗原
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