TNIP1 抗体
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北京 101111
Quick Overview for TNIP1 抗体 (ABIN1387564)
抗原
See all TNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TNIP1
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亚型
- IgG
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anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 526-636) antibody
TNIP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) antibodyTNIP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 1-636) antibodyTNIP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 99-148) antibodyTNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (N-Term) antibodyTNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (C-Term) antibodyTNIP1 适用: 人, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB28148 unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6980398, (2020) (PubMed).
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: "A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6980398, (2020) (PubMed).
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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别名
- TNIP1
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背景
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Synonyms: ABIN 1, ABIN-1, abin1, HIV-1 Nef interacting protein Nip40-1, TNFAIP3 interacting protein 1, HIV-1 Nef interacting protein, HIV-1 Nef-interacting protein, hVAN, KIAA0113, NAF 1, NAF-1, NAF1, Nef-associated factor 1, Nef-associated factor 1 SNP, Nip 40-1, Nip40-1, TNFAIP3 interacting protein 1, TNFAIP3-interacting protein 1, TNIP 1, TNIP-1, Tnip1, TNIP1_HUMAN, VAN, Virion associated nuclear shuttling protein, Virion-associated nuclear shuttling protein.
Background: Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NF_B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.
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途径
- Activation of Innate immune Response
抗原
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