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ERN1 抗体 (AA 252-260)

Name: ERN1 抗体 (AA 252-260)
SKU: ABIN1387555
Availability: OutOfStock

Cited in 6+ publications. This 兔多克隆 anti-ERN1 antibody specifically detects ERN1 in WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠, 大鼠和 Pig samples.

Paraformaldehyde-fixed, paraffin embedded Rat brain Antigen retrieval by boiling in sodium citrate buffer (pH6. (ERN1 抗体 (AA 252-260))

IHC (p)

1 image

(6 references)

产品编号 ABIN1387555

发货至: 中国

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中国
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Quick Overview for ERN1 抗体 (AA 252-260) (ABIN1387555)

抗原

See all ERN1 抗体

ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

适用

人, 小鼠, 大鼠, Pig

宿主

兔

克隆类型

多克隆

标记

This ERN1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product ERN1 Primary Antibody

抗原表位
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AA 252-260

交叉反应

人, 小鼠, Pig, 大鼠

预测反应

Dog,Cow,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human IRE1a

亚型

IgG
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 8D12 unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibody
ERN1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9F2 unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibody
ERN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibody
ERN1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1F12 unconjugated Recombinant Antibody

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibody
ERN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5220 unconjugated Recombinant Antibody

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibody
Verified ERN1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibody
ERN1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibody (FITC)
ERN1 适用: 人, 小鼠, 大鼠, Pig WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 493-561) antibody
ERN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Chen, Wang, Chen, Wang, Gui, Dai, Fang, Zhang, Lu: "Influence of resveratrol on endoplasmic reticulum stress and expression of adipokines in adipose tissues/adipocytes induced by high-calorie diet or palmitic acid." in: Endocrine, Vol. 55, Issue 3, pp. 773-785, (2017) (PubMed).

He, Xu, Gou, Yuan, Liao, Chen, Fan, Xie, Deng, Zhang, Chen, Zhao: "CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication." in: Frontiers in microbiology, Vol. 8, pp. 2129, (2017) (PubMed).

Jiang, Yun, Shi, Niu, Gao, Xie, Yu: "Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress." in: American journal of physiology. Cell physiology, Vol. 310, Issue 9, pp. C755-63, (2016) (PubMed).

Xu, Su, Song, Shi, Fu, Hu, Xia, Song, Song: "Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release." in: Chemical research in toxicology, Vol. 28, Issue 6, pp. 1326-37, (2015) (PubMed).

Li, Han, Shi: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).

Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." in: Neuroscience, Vol. 277, pp. 132-8, (2014) (PubMed).
抗原

ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

别名

IRE1a

背景

Synonyms: IRE1, IRE1P, IRE1a, hIRE1p, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, ERN1
Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

基因ID

2081

UniProt

O75460

途径

ER-Nucleus Signaling, Unfolded Protein Response