Peroxiredoxin 2 抗体 (AA 131-198)
Quick Overview for Peroxiredoxin 2 抗体 (AA 131-198) (ABIN1387547)
抗原
See all Peroxiredoxin 2 (PRDX2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 131-198
-
交叉反应
- 人, 大鼠
-
预测反应
- Mouse,Dog,Cow,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Peroxiredoxin-2
-
亚型
- IgG
-
-
anti-Peroxiredoxin 2 (PRDX2) (AA 1-198) antibody
PRDX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E10-2D2 unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 6-164) antibodyPRDX2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 6-164) antibodyPRDX2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (C-Term) antibodyPRDX2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 2-65) antibodyPRDX2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) antibodyPRDX2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 1-142) antibodyPRDX2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) antibodyPRDX2 适用: 人 WB, IP, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 169-198), (C-Term) antibodyPRDX2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB20888 unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 1-198) antibodyPRDX2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- Peroxiredoxin 2 (PRDX2)
-
别名
- Peroxiredoxin 2
-
背景
-
Synonyms: MGC4104, Natural killer cell enhancing factor B, Natural killer cell-enhancing factor B, Natural Killer Enhancing Factor B, NKEF B, NKEF-B, NKEFB, Peroxiredoxin-2, PRDX 2, PRDX2, PRDX2_HUMAN, PRP, PRX2, PRXII, TDPX1, Thiol Specic Antioxidant 1, Thiol specic antioxidant protein, Thiol-specic antioxidant protein, Thioredoxin Dependent Peroxide Reductase 1, Thioredoxin Peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Torin, TPX1, TSA.
Background: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
-
基因ID
- 7001
抗原
-
