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NPM1 抗体 (AA 21-120)

Name: NPM1 抗体 (AA 21-120)
SKU: ABIN1387533
Availability: OutOfStock

This anti-NPM1 antibody is a 兔多克隆 antibody detecting NPM1 in WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Formalin-fixed and paraffin embedded human kidney labeled with Anti-Nucleophosmin Polyclonal Antibody, Unconjugated at 1:300 followed by conjugation to the secondary antibody and DAB staining. (NPM1 抗体 (AA 21-120))

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Nucleophosmin Polyclonal Antibody, Unconjugated (ABIN1387533) at 1:200 followed by conjugation to the secondary antibody and DAB staining (NPM1 抗体 (AA 21-120))

IHC

L1 rat kidney lysate L2 rat brain lysates probed with Anti Nucleophosmin Polyclonal Antibody, Unconjugated (ABIN1387533) at 1:200 overnight at 4 °C. (NPM1 抗体 (AA 21-120))

SDS

3 images

(1 reference)

产品编号 ABIN1387533

发货至: 中国

Quick Overview for NPM1 抗体 (AA 21-120) (ABIN1387533)

抗原

See all NPM1 抗体

NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This NPM1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product NPM1 Primary Antibody

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AA 21-120

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Nucleophosmin

亚型

IgG
anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 1-294) antibody
NPM1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 250-298), (C-Term) antibody
NPM1 适用: 人 WB, IF, IHC (p), IP, FACS 宿主: 兔 Polyclonal unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 20-154) antibody
NPM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 212-292) antibody
NPM1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 185-287) antibody
NPM1 适用: 人 WB, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal NPM1-3286 unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (pThr199) antibody
NPM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (C-Term) antibody
Verified NPM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 185-287) antibody
NPM1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rNPM1-1901 unconjugated Recombinant Antibody

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 185-287) antibody
NPM1 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal NPM1-1902 unconjugated

anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 198-226) antibody
NPM1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Jiang, Xie, Cai, Ren, Ma: "Effects of hepatitis C virus core protein and nonstructural protein 4B on the Wnt/β-catenin pathway." in: BMC microbiology, Vol. 17, Issue 1, pp. 124, (2017) (PubMed).
抗原

NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

别名

Nucleophosmin

背景

Synonyms: B23, NPM, Nucleophosmin, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1
Background: Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.

基因ID

4869

UniProt

P06748

途径

Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly