Proteoglycan 4 抗体 (AA 1151-1250)
Quick Overview for Proteoglycan 4 抗体 (AA 1151-1250) (ABIN1387463)
抗原
See all Proteoglycan 4 (PRG4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1151-1250
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交叉反应
- 小鼠, 兔, 大鼠
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预测反应
- Human,Dog,Cow
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Lubricin/SZP
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亚型
- IgG
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anti-Proteoglycan 4 (PRG4) (AA 1151-1241) antibody
PRG4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteoglycan 4 (PRG4) (AA 176-210) antibodyPRG4 适用: 人 WB, IF 宿主: 兔 Polyclonal RB57887 unconjugated
anti-Proteoglycan 4 (PRG4) (AA 1305-1404) antibodyPRG4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Proteoglycan 4 (PRG4) (AA 25-156) antibodyPRG4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteoglycan 4 (PRG4) (AA 1264-1363) antibodyPRG4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Proteoglycan 4 (PRG4)
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别名
- Lubricin/SZP
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背景
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Synonyms: Superficial zone proteoglycan, articular superficial zone protein, bG174L6.2, CACP, camptodactyly arthropathy coxa vara pericarditis syndrome gene, FLJ32635, HAPO, Jacobs camptodactyly-arthropathy-pericarditis syndrome gene, JCAP, megakaryocyte stimulating factor, MSF, PRG 4, PRG4, proteoglycan 4, Proteoglycan4, Superficial zone proteoglycan, SZP.
Background: Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
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基因ID
- 10216
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UniProt
- Q92954
抗原
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