ZFHX3 抗体 (AA 301-400)
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北京 101111
Quick Overview for ZFHX3 抗体 (AA 301-400) (ABIN1387456)
抗原
See all ZFHX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ATBF1
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亚型
- IgG
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anti-Zinc Finger Homeobox 3 (ZFHX3) (AA 2811-2910) antibody
ZFHX3 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Zinc Finger Homeobox 3 (ZFHX3) antibodyZFHX3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Homeobox 3 (ZFHX3) (AA 2811-2910) antibodyZFHX3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Homeobox 3 (ZFHX3) (AA 517-787) antibodyZFHX3 适用: 人 ELISA, IHC, IHC (p), WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
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别名
- ATBF1
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背景
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Synonyms: Alpha fetoprotein enhancer binding protein, AT binding transcription factor 1, AT mot binding factor, ATBT, ZFHX3, ZFHX3_HUMAN.
Background: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (13). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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