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Cullin 5 抗体 (AA 701-780)

This anti-Cullin 5 antibody is a 兔 多克隆 antibody detecting Cullin 5 in ELISA, IF (cc), IF (p), IHC (p), ICC 和 IHC (fro). Suitable for 人.
产品编号 ABIN1387404
发货至: 中国

Quick Overview for Cullin 5 抗体 (AA 701-780) (ABIN1387404)

抗原

See all Cullin 5 (CUL5) 抗体
Cullin 5 (CUL5)

适用

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宿主

  • 37
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克隆类型

  • 38
多克隆

标记

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This Cullin 5 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 701-780

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Cullin 5

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Cullin 5 (CUL5)

    别名

    Cullin 5

    背景

    Synonyms: CUL 5, CUL-5, CUL5, CUL5_HUMAN, Cullin-5, Cullin5, VACM 1, VACM-1, VACM1, Vasopressin activated calcium mobilizing receptor 1, Vasopressin activated calcium mobilizing receptor, Vasopressin-activated calcium-mobilizing receptor 1.

    Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

    基因ID

    1729

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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