DDX5 抗体 (AA 301-430)
Quick Overview for DDX5 抗体 (AA 301-430) (ABIN1387377)
抗原
See all DDX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-430
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DDX5/p68 RNA Helicase
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
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别名
- DDX5
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背景
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Synonyms: ATP dependent RNA helicase DDX5, DDX 5, Ddx5, DDX5_HUMAN, DEAD Asp Glu Ala Asp box helicase 5, DEAD Asp Glu Ala Asp box polypeptide 5, DEAD box 5, DEAD box protein 5, DEAD/H Asp Glu Ala Asp/His box polypeptide 5 RNA helicase, 68kD, DEAD/H Asp Glu Ala Asp/His box polypeptide 5, DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 5 RNA helicase 68 kDa, DEAD/H box-5 RNA helicase 68kD, DKFZp686J01190, G17P1, HELR, HLR 1, HLR1, HUMP68, P68, P68, p68 RNA helicase, Probable ATP dependent RNA helicase DDX5, Probable ATP-dependent RNA helicase DDX5, RNA helicase 68kD, RNA helicase p68, RNA-dependent ATPase.
Background: p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.
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基因ID
- 1655
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UniProt
- P17844
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
抗原
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