UBE2K 抗体 (AA 51-150)
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北京 101111
Quick Overview for UBE2K 抗体 (AA 51-150) (ABIN1387369)
抗原
See all UBE2K 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HIP2
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 109-139) antibody
UBE2K 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4144 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-100) antibodyUBE2K 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 2-200) antibodyUBE2K 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyVerified UBE2K 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, Pig, 猴, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-40) antibodyUBE2K 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 108-157) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, Pig, 猴, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (N-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, Pig, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 36-85) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, Pig, 猴, Hamster, Bat, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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别名
- HIP2
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背景
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Synonyms: LIG, HIP2, HYPG, UBC1, E2-25K, Ubiquitin-conjugating enzyme E2 K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.
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基因ID
- 3093
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UniProt
- P61086
抗原
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