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GUCA2A 抗体 (AA 22-115)

This anti-GUCA2A antibody is a 兔 多克隆 antibody detecting GUCA2A in IF (cc), IF (p), ELISA, ICC, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1387343
发货至: 中国

Quick Overview for GUCA2A 抗体 (AA 22-115) (ABIN1387343)

抗原

See all GUCA2A 抗体
GUCA2A (Guanylate Cyclase Activator 2A (Guanylin) (GUCA2A))

适用

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宿主

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克隆类型

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多克隆

标记

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This GUCA2A antibody is un-conjugated

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 22-115

    预测反应

    Human,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Guanylin

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GUCA2A (Guanylate Cyclase Activator 2A (Guanylin) (GUCA2A))

    别名

    Guanylin

    背景

    Synonyms: GapI, GCAP-I, Guanylate cyclase activating protein 1, Guanylate cyclase activator 2A guanylin 2 intestinal heat-stable, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, Guanylin, GUC2A_HUMAN, GUCA 2, GUCA2, GUCA2A, STARA.

    Background: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.

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