LYL1 抗体 (AA 151-250)
Quick Overview for LYL1 抗体 (AA 151-250) (ABIN1387276)
抗原
See all LYL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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交叉反应
- 人
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预测反应
- Mouse,Rat,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LYL1
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亚型
- IgG
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anti-LYL1 (LYL1) (AA 1-280) antibody
LYL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-LYL1 (LYL1) (N-Term) antibodyLYL1 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-LYL1 (LYL1) (AA 212-244) antibodyLYL1 适用: 人 WB 宿主: 兔 Polyclonal RB54126 unconjugated
anti-LYL1 (LYL1) (AA 35-84) antibodyLYL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LYL1 (LYL1) (Center) antibodyLYL1 适用: 人, 小鼠, 大鼠, Pig, 小鸡, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LYL1
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别名
- Lyl1
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背景
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Synonyms: Lyl1; Lymphoblastic leukemia derived sequence 1; Protein lyl 1.
Background: The Lyl1 gene encodes a basic helixloophelix transcription factor involved in T-cell acute lymphoblastic leukemia. The expression of Lyl1 is at higher levels in the majority of cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow. Lyl1 is highly expressed in most AML cell lines.Lyl-1, TAL1 and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia. TAL1, also designated SCL, is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. TAL2 is a protein involved in T cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and T cell receptor chain genes. TAL2 includes a helix-loop-helix protein dimerization and DNA-binding domain that is homologous to TAL1 and Lyl-1 proto-oncogenes. Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein. Endogenous Lyl-1 exists in complex with E2å proteins. Lyl-1 and E2å protein can form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. Lyl-1 is involved in a chromosomal aberration which causes a form of T cell acute lymphoblastic leukemia (T-ALL).
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基因ID
- 4066
抗原
-
