C3orf15 抗体
Quick Overview for C3orf15 抗体 (ABIN1387183)
抗原
See all C3orf15 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human AAT1/C3orf15
-
亚型
- IgG
-
-
anti-Chromosome 3 Open Reading Frame 15 (C3orf15) (AA 1-767) antibody
C3orf15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Chromosome 3 Open Reading Frame 15 (C3orf15) (AA 81-130) antibodyC3orf15 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 3 Open Reading Frame 15 (C3orf15) (AA 29-181) antibodyC3orf15 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 3 Open Reading Frame 15 (C3orf15) (N-Term) antibodyC3orf15 适用: 人, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- C3orf15 (Chromosome 3 Open Reading Frame 15 (C3orf15))
-
别名
- C3orf15
-
背景
-
Synonyms: AAT 1; AAT-1; AAT1; AAT1 alpha; AAT1_HUMAN; AAT1alpha; AMY 1 associating protein expressed in testis 1; AMY-1-associating protein expressed in testis 1; Chromosome 3 open reading frame 15; MYCBP binding protein.
Background: The c-Myc proto-oncogene plays a significant role in cell proliferation, differentiation, transformation and apoptosis. A novel c-Myc binding protein, MYCBP (also designated AMY-1), binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. MYCBP translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. MYCBP and AAT-1 (AMY-1-associating protein expressed in testis 1) have been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP and AAT-1 in spermatogenesis. Expression of the AAT-1 gene is regulated by two different promoters, which result in various isoforms. One promoter generates expression of the AAT-1, AAT-1å, AAT-1 and AAT-1© isoforms, which are specifically expressed in testis, while the other promoter generates AAT-1L, AAT-1M and AAT-1S, which are differentially expressed.
抗原
-
