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BEND7 抗体

This anti-BEND7 antibody is a 兔 多克隆 antibody detecting BEND7 in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1387161
发货至: 中国

Quick Overview for BEND7 抗体 (ABIN1387161)

抗原

BEND7 (BEN Domain Containing 7 (BEND7))

适用

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人, 小鼠, 大鼠

宿主

  • 20

克隆类型

  • 20
多克隆

标记

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This BEND7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human C10orf30/BEND7

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    BEND7 (BEN Domain Containing 7 (BEND7))

    别名

    BEND7

    背景

    Synonyms: BEN domain-containing protein 7, BEND7, Chromosome 10 open reading frame 30, FLJ40283, MGC35247, BEND7_HUMAN.

    Background: BEND7 is a 519 amino acid protein that contains a BEN domain. BEN domain mediates proteinDNA and proteinprotein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. BEND7 exists as three independently spiced isoforms and the gene that encodes BEND7 maps to chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.

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