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EML3 抗体

EML3 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387136
发货至: 中国
  • 抗原 See all EML3 抗体
    EML3 (Echinoderm Microtubule Associated Protein Like 3 (EML3))
    适用
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This EML3 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EML3
    亚型
    IgG
    Top Product
    Discover our top product EML3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    EML3 (Echinoderm Microtubule Associated Protein Like 3 (EML3))
    别名
    EML3 (EML3 产品)
    别名
    BC022146 antibody, ELP95 antibody, RGD1311368 antibody, echinoderm microtubule associated protein like 3 antibody, Eml3 antibody, EML3 antibody
    背景

    Synonyms: Echinoderm microtubule associated protein like 3, ELP 95, EMAP 3, EMAP3, EMAP-3, EML 3, EML3, EML-3, FLJ 35827, MGC 111422, EMAL3_HUMAN.

    Background: At the onset of mitosis, assembly of the mitotic spindle requires a global change in the activity of microtubule-binding proteins. EML3 (Echinoderm microtubule-associated protein-like 3) is a 896 amino acid protein that likely modifies microtubule dynamics by making them longer. Through colocalization with spindle microtubules during mitosis, EML3 plays a role in correct metaphase chromosome alignment. EML3 contains a nuclear localization signal and a microtubule-binding domain. The gene encoding EML3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    基因ID
    256364
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