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EML3 抗体

The 兔 多克隆 anti-EML3 antibody is suitable to detect EML3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF (p) 和 IHC (p).
产品编号 ABIN1387136
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EML3 抗体 (ABIN1387136)

抗原

See all EML3 抗体
EML3 (Echinoderm Microtubule Associated Protein Like 3 (EML3))

适用

  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 5

克隆类型

  • 5
多克隆

标记

  • 5
This EML3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EML3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    EML3 (Echinoderm Microtubule Associated Protein Like 3 (EML3))

    别名

    EML3

    背景

    Synonyms: Echinoderm microtubule associated protein like 3, ELP 95, EMAP 3, EMAP3, EMAP-3, EML 3, EML3, EML-3, FLJ 35827, MGC 111422, EMAL3_HUMAN.

    Background: At the onset of mitosis, assembly of the mitotic spindle requires a global change in the activity of microtubule-binding proteins. EML3 (Echinoderm microtubule-associated protein-like 3) is a 896 amino acid protein that likely modifies microtubule dynamics by making them longer. Through colocalization with spindle microtubules during mitosis, EML3 plays a role in correct metaphase chromosome alignment. EML3 contains a nuclear localization signal and a microtubule-binding domain. The gene encoding EML3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    基因ID

    256364
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