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E4F1 抗体

E4F1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387131
发货至: 中国
  • 抗原 See all E4F1 抗体
    E4F1 (E4F Transcription Factor 1 (E4F1))
    适用
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    • 4
    克隆类型
    • 8
    • 2
    多克隆
    标记
    • 10
    This E4F1 antibody is un-conjugated
    应用范围
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human E4F1
    亚型
    IgG
    Top Product
    Discover our top product E4F1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    E4F1 (E4F Transcription Factor 1 (E4F1))
    别名
    E4F1 (E4F1 产品)
    别名
    e4f antibody, MGC147041 antibody, E4F antibody, Dnase1l2 antibody, zgc:114190 antibody, E4F transcription factor 1 antibody, E4F transcription factor 1 S homeolog antibody, E4F1 antibody, e4f1 antibody, e4f1.S antibody, E4f1 antibody
    背景

    Synonyms: E4F, E4F transcription factor 1, isoform CRA_b, P120E4F transcription factor, E4F1_HUMAN.

    Background: E4F1, also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains nine C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.

    基因ID
    1877
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