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PROCR 抗体

This anti-PROCR antibody is a 兔 多克隆 antibody detecting PROCR in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1387092
发货至: 中国

Quick Overview for PROCR 抗体 (ABIN1387092)

抗原

See all PROCR 抗体
PROCR (Protein C Receptor, Endothelial (PROCR))

适用

  • 55
  • 14
  • 14
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 57
  • 13
  • 8

克隆类型

  • 58
  • 20
多克隆

标记

  • 50
  • 14
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PROCR antibody is un-conjugated

应用范围

  • 59
  • 41
  • 23
  • 19
  • 17
  • 11
  • 11
  • 6
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EPCR/CD201

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Zhao, Ding, Liu, Yin, Zhang, Ma: "Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5515-5522, (2017) (PubMed).

  • 抗原

    PROCR (Protein C Receptor, Endothelial (PROCR))

    别名

    EPCR

    背景

    Synonyms: Activated protein C receptor, APC receptor, APCR, CCCA, CCD41, CD201 antigen, centrocyclin, Endothelial cell protein C receptor, MGC23024, PROCR, EPCR_HUMAN, CD201.

    Background: EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is an N glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. It is expressed strongly in the endothelial cells of arteries and veins in heart and lung. It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear.

    基因ID

    10544
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