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MARCH3 抗体

MARCH3 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387033
发货至: 中国
  • 抗原 See all MARCH3 抗体
    MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))
    适用
    • 44
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    人, 小鼠, 大鼠
    宿主
    • 41
    • 3
    克隆类型
    • 42
    • 2
    多克隆
    标记
    • 15
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    This MARCH3 antibody is un-conjugated
    应用范围
    • 43
    • 20
    • 12
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MARCH3
    亚型
    IgG
    Top Product
    Discover our top product MARCH3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))
    别名
    MARCH3 (MARCH3 产品)
    别名
    6330411I15Rik antibody, A530081L18Rik antibody, AI843639 antibody, MARCH-III antibody, RNF173 antibody, membrane-associated ring finger (C3HC4) 3 antibody, membrane associated ring-CH-type finger 3 antibody, March3 antibody, MARCH3 antibody
    背景

    Synonyms: E3 ubiquitin-protein ligase MARCH3, FLJ20096, MARCH-III, March3, MARH3_HUMAN, Membrane associated ring finger C3HC4 3, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, RING finger protein 173, RNF173.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH3 (membrane-associated ring finger (C3HC4) 3), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger. Involved in the pathway of protein modification, MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events.

    基因ID
    115123
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