ANKS6 抗体
Quick Overview for ANKS6 抗体 (ABIN1386931)
抗原
See all ANKS6 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ANKS6
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ANKS6 (Ankyrin Repeat and Sterile alpha Motif Domain Containing 6 (ANKS6))
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别名
- ANKS6
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背景
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Synonyms: ANKRD14, Anks6, ANKS6_HUMAN, ankyrin repeat and SAM domain containing protein 6, Ankyrin repeat and SAM domain-containing protein 6, ankyrin repeat domain 14, ankyrin repeat domain containing protein 14, Ankyrin repeat domain-containing protein 14, SAM domain containing protein 6, SAM domain-containing protein 6, SamCystin, SAMD6, sterile alpha mot domain containing 6, sterile alpha mot domain containing protein 6, Sterile alpha mot domain-containing protein 6.
Background: ANKS6, also known as ankyrin repeat domain-containing protein 14, SAMD6 (sterile alpha motif domain-containing protein 6), SamCystin or PKDR1, is an 871 amino acid phosphoprotein that contains eleven ANK repeats, one SAM domain and exists as three alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 9q22.33, ANKS6 is necessary for renal function and is linked to renal cyst formation in polycystic kidney disease. ANKS6 interacts with BICC1, another protein linked to polycystic kidney disease, and both co-localize to the same cell region. ANKS6 is involved in proteinprotein interactions with both itself as well as BICC1, and both proteins function in a molecular pathway that is linked to cystogenesis. ANKS6 may also be associated with dental anomolies.
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基因ID
- 203286
抗原
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