HIP1R 抗体
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- 抗原 See all HIP1R 抗体
- HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIP1R antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HIP1R/HIP12/HIP3
- 亚型
- IgG
- Top Product
- Discover our top product HIP1R Primary Antibody
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anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 1-1068) antibody
HIP1R 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 1-1068) antibodyHIP1R 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 969-1066) antibodyHIP1R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 304-487) antibodyHIP1R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (N-Term) antibodyHIP1R 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 771-1012) antibodyHIP1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 98-126), (N-Term) antibodyHIP1R 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18066 unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) antibodyHIP1R 适用: 人 WB 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 300-600) antibodyHIP1R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Interacting Protein 1 Related (HIP1R) (AA 105-133), (N-Term) antibodyHIP1R 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))
- 别名
- HIP12 (HIP1R 产品)
- 别名
- HIP12 antibody, HIP3 antibody, ILWEQ antibody, AA410023 antibody, mKIAA0655 antibody, HIP1R antibody, hip1r antibody, hip3 antibody, hip12 antibody, ilweq antibody, DKFZp469N2015 antibody, hip1 antibody, MGC78813 antibody, huntingtin interacting protein 1 related antibody, huntingtin interacting protein 1 related b antibody, huntingtin interacting protein 1 related L homeolog antibody, HIP1R antibody, Hip1r antibody, hip1rb antibody, hip1r antibody, hip1r.L antibody
- 背景
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Synonyms: Hip1 related, HIP12, HIP3, Huntingtin Interacting Protein 1 Related, HIP1R, Huntingtin interacting protein 12, HIP1R_HUMAN.
Background: Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking, the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
- 基因ID
- 9026
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