PDZD4 抗体
Quick Overview for PDZD4 抗体 (ABIN1386897)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PDZK4
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亚型
- IgG
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anti-PDZ Domain Containing 4 (PDZD4) (AA 536-585) antibody
PDZD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 4 (PDZD4) (AA 113-141), (N-Term) antibodyPDZD4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB32936 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PDZD4 (PDZ Domain Containing 4 (PDZD4))
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别名
- PDZK4
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背景
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Synonyms: FERM and PDZ domain containing protein 2, PDZ domain containing protein 4, PDZ domain containing protein 5C, PDZ domain containing 4 PDZD5C, PDZK4, PDZK5C,FRPD2_HUMAN.
Background: PDZK4, also known as PDZRN4L (PDZ domain-containing RING finger protein 4-like protein) or LU1, is a 769 amino acid coiled-coil protein that contains one PDZ (DHR) domain. Encoded by a gene that maps to human chromosome Xq28, PDZK4 is conserved in dog, cow, mouse, rat and zebrafish. PDZK4 localizes to cytoplasm and is expressed specifically in adult and fetal brain. PDZK4 functions as an oncogene and is up-regulated in synovial carcinomas. Treatment of synovial sarcoma cells with small interfering RNA (siRNA) inhibits PDZK4 expression, resulting in tumor-cell growth suppression, suggesting that inappropriate expression of PDZK4 may play a role synovial sarcoma cell proliferation.The exact function of FRMPD2 is unknown. The protein contains a FERM domain: such structures are often involved in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.
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基因ID
- 143162
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UniProt
- Q68DX3
抗原
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