BRMS1 抗体 (AA 151-246)
-
- 抗原 See all BRMS1 抗体
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
-
抗原表位
- AA 151-246
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This BRMS1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BRMS1
- 亚型
- IgG
- Top Product
- Discover our top product BRMS1 Primary Antibody
-
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibody
BRMS1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2D4-2G11 unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 90-210) antibodyBRMS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (N-Term) antibodyBRMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) antibodyBRMS1 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 48-77), (N-Term) antibodyBRMS1 适用: 人 WB 宿主: 兔 Polyclonal RB40250 unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (C-Term) antibodyBRMS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibodyBRMS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibodyBRMS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (Center) antibodyBRMS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- 别名
- BRMS1 (BRMS1 产品)
- 背景
-
Synonyms: Breast cancer metastasis suppressor 1, Breast cancer metastasis-suppressor 1, BRMS-1, BRMS1_HUMAN, DKFZp564A063, MGC95128, AV003220, AW554636.
Background: Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-_B activity.
-
