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OLIG1 抗体 (AA 121-220)

This anti-OLIG1 antibody is a 兔 多克隆 antibody detecting OLIG1 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN1386861
发货至: 中国

Quick Overview for OLIG1 抗体 (AA 121-220) (ABIN1386861)

抗原

See all OLIG1 抗体
OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

适用

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  • 1
大鼠

宿主

  • 63
  • 6
  • 1

克隆类型

  • 59
  • 9
  • 1
多克隆

标记

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This OLIG1 antibody is un-conjugated

应用范围

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  • 27
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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
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    AA 121-220

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OLIG1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

    别名

    OLIG1

    背景

    Synonyms: Oligo 1, Oligo1, Oligodendrocyte lineage transcription factor 1, Oligodendrocyte specic bHLH transcription factor 1, Oligodendrocyte transcription factor 1. Basic domain helix loop helix protein class B 6, Basic domain helix loop helix protein class B6, BHLH B6, BHLHB 6, BHLHB6, bHLHe21, Class B basic helix-loop-helix protein 6, Class E basic helix-loop-helix protein 21, Olig 1, Olig1, OLIG1_HUMAN.

    Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

    基因ID

    116448

    UniProt

    Q8TAK6
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