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FBXL12 抗体 (AA 171-270)

This anti-FBXL12 antibody (ABIN1386844) is a Rabbit Polyclonal antibody detecting FBXL12 in WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro). Suitable for Human.
产品编号 ABIN1386844
发货至: 中国

Quick Overview for FBXL12 抗体 (AA 171-270) (ABIN1386844)

抗原

See all FBXL12 抗体
FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

适用

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宿主

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克隆类型

  • 18
多克隆

标记

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This FBXL12 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 171-270

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FbxL12

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

    别名

    FbxL12

    背景

    Synonyms: F box and leucine rich repeat protein 12, F box protein FBL12, F box/LRR repeat protein 12, FBXL 12, FLJ20188, FXL12_HUMAN.

    Background: F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚,B-å, and -catenin, for proteasomal degradation. FBL12 (F-box and leucine-rich repeat protein 12), also designated FBXL12, is a 326 amino acid protein that contains one F-box domain, five LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. FBL12 interacts with both Skp1 and CUL-1, and is encoded by a gene that maps to human chromosome 19p13.2.

    基因ID

    54850

    途径

    SARS-CoV-2 Protein Interactome
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