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FBXW8 抗体 (AA 181-280)

This anti-FBXW8 antibody is a 兔 多克隆 antibody detecting FBXW8 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN1386823
发货至: 中国

Quick Overview for FBXW8 抗体 (AA 181-280) (ABIN1386823)

抗原

See all FBXW8 抗体
FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

适用

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大鼠

宿主

  • 30
  • 1

克隆类型

  • 31
多克隆

标记

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This FBXW8 antibody is un-conjugated

应用范围

  • 30
  • 12
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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 7
    • 2
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    AA 181-280

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FBXW8/FBXO29

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

    别名

    FBXW8

    背景

    Synonyms: F box/WD repeat containing protein 8; F box and WD40 domain containing protein 8; F-box only protein 29; F box only protein 29; FBW6; FBW8; FBX29; FBXO29; FBXW6; FBXW8_HUMAN.

    Background: FBXO29, also designated F-box/WD repeat-containing protein 8 (FBXW8), is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family. FBXO29 also contains five WD repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and -catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO29 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation. FBXO29 exists as two isoforms as a result of alternative splicing events.

    基因ID

    26259
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