FBXW8 抗体 (AA 181-280)
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北京 101111
Quick Overview for FBXW8 抗体 (AA 181-280) (ABIN1386823)
抗原
See all FBXW8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-280
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FBXW8/FBXO29
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亚型
- IgG
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anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 270-299) antibody
FBXW8 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28550 unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 499-598) antibodyFBXW8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 273-303), (Middle Region) antibodyFBXW8 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) antibodyFBXW8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) antibodyFBXW8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (C-Term) antibodyFBXW8 适用: 人, Cow, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 504-553) antibodyFBXW8 适用: 人, Cow, 兔, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (Middle Region) antibodyFBXW8 适用: 人, 大鼠, 小鼠, Cow, 兔, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
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别名
- FBXW8
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背景
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Synonyms: F box/WD repeat containing protein 8; F box and WD40 domain containing protein 8; F-box only protein 29; F box only protein 29; FBW6; FBW8; FBX29; FBXO29; FBXW6; FBXW8_HUMAN.
Background: FBXO29, also designated F-box/WD repeat-containing protein 8 (FBXW8), is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family. FBXO29 also contains five WD repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and -catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO29 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation. FBXO29 exists as two isoforms as a result of alternative splicing events.
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基因ID
- 26259
抗原
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