PANK1 抗体
Quick Overview for PANK1 抗体 (ABIN1386809)
抗原
See all PANK1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PANK1
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亚型
- IgG
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anti-Pantothenate Kinase 1 (PANK1) antibody
PANK1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 310-409) antibodyPANK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 462-582) antibodyPANK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 1-373) antibodyPANK1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 298-500) antibodyPANK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 1-373) antibodyPANK1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 1 (PANK1) (AA 332-360) antibodyPANK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5483 unconjugated
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应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- PANK1 (Pantothenate Kinase 1 (PANK1))
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别名
- PANK1
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背景
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Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.
Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
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基因ID
- 53354
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UniProt
- Q8TE04
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途径
- Ribonucleoside Biosynthetic Process
抗原
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