DPYSL2 抗体 (pSer518, pThr514)
Quick Overview for DPYSL2 抗体 (pSer518, pThr514) (ABIN1386795)
抗原
See all DPYSL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer518, pThr514
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518
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亚型
- IgG
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anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-572) antibody
DPYSL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 470-571) antibodyDPYSL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) antibodyDPYSL2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 400-500) antibodyKO Validated DPYSL2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (Thr509) antibodyDPYSL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 480-529) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 463-492) antibodyDPYSL2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 33CT11-40-3 unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-100) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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别名
- Crmp2
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背景
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Synonyms: CRMP2 phospho T514 + S518, CRMP2 phospho T514+S518, CRMP-2phospho Thr514+S518, p-CRMP2Thr514+S518, CRMP2/Dpysl2DRP 2, Collapsin response mediator protein 2, Collapsin response mediator protein hCRMP 2, CRAM, CRMP 2, DHPRP 2, DHPRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form,Dihydropyrimidinase related protein 2, DPYL 2, DPYL2, DPYSL 2, DPYSL2, DRP 2, DRP2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, Ulip2.
Background: Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.
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基因ID
- 1808
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途径
- Regulation of Cell Size
抗原
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