DIRC2 抗体 (AA 51-150)
Quick Overview for DIRC2 抗体 (AA 51-150) (ABIN1386794)
抗原
See all DIRC2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 51-150
-
交叉反应
- 人, 大鼠
-
预测反应
- Mouse,Dog,Sheep,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human DIRC2
-
亚型
- IgG
-
-
anti-Disrupted in Renal Carcinoma 2 (DIRC2) (AA 202-229) antibody
DIRC2 适用: 人 WB 宿主: 兔 Polyclonal RB42515 unconjugated
anti-Disrupted in Renal Carcinoma 2 (DIRC2) (AA 216-265) antibodyDIRC2 适用: 人, 小鼠, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
-
别名
- Dirc2
-
背景
-
Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.
Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
-
基因ID
- 84925
抗原
-
