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MYF5 抗体 (pSer49)

This anti-MYF5 antibody is a 兔 多克隆 antibody detecting MYF5 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1386790
发货至: 中国

Quick Overview for MYF5 抗体 (pSer49) (ABIN1386790)

抗原

See all MYF5 抗体
MYF5 (Myogenic Factor 5 (MYF5))

适用

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宿主

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克隆类型

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多克隆

标记

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This MYF5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer49

    预测反应

    Human,Mouse,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human MYF5 around the phosphorylation site of Ser49

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MYF5 (Myogenic Factor 5 (MYF5))

    别名

    Myf5

    背景

    Synonyms: Myf5 phospho S49, Myf5 phospho Ser49, p-Myf5phospho S49, p-Myf5phospho Ser49, Myf-5 bHLHc2, Class C basic helix loop helix protein 2, Class C basic helix-loop-helix protein 2, Myf 5, Myf-5, Myf5, MYF5_HUMAN, Myogenic factor 5.

    Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.

    基因ID

    4617

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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