MLC1 抗体 (AA 321-377)
(1 reference)Quick Overview for MLC1 抗体 (AA 321-377) (ABIN1386787)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 321-377
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MLC1
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亚型
- IgG
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anti-MLC1 (Middle Region) antibody
适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MLC1 (AA 1-49) antibody适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MLC1 (AA 179-193) antibodyVerified 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-MLC1 (AA 179-228) antibody适用: 人, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-MLC1 (C-Term) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
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: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
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- MLC1
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背景
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Synonyms: KIAA0027, LVM, Megalencephalic leukoencephalopathy with subcortical cysts 1, Membrane protein MLC1, MLC, MLC-1, MLC1_HUMAN, VL, WKL1.
Background: MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.
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基因ID
- 23209
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UniProt
- Q15049
抗原
-
