Glucose-6-Phosphate Dehydrogenase 抗体 (AA 321-420)
Quick Overview for Glucose-6-Phosphate Dehydrogenase 抗体 (AA 321-420) (ABIN1386785)
抗原
See all Glucose-6-Phosphate Dehydrogenase (G6PD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 321-420
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预测反应
- Human,Mouse,Rat,Dog,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human G6PDH
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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别名
- G6PDH
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背景
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Synonyms: 6 phosphogluconolactonase, 6-phosphogluconolactonase, 6PGL, H6PD, DKFZp686A01246, G6PD H form, G6PDH, G6PE_HUMAN, GDH, H6PD, GDH/6PGL endoplasmic bunctional protein, Glucose 1 dehydrogenase, Glucose 6 phosphate dehydrogenase salivary, Glucose dehyrogenase, Gpd1, H6pd, Hexose 6 phosphate dehydrogenase, Hexose-6-phosphate dehydrogenase, MGC87643.
Background: H6PD (hexose-6-phosphate dehydrogenase, GDH/6PGL endoplasmic bifunctional protein) is a 789 amino acid protein encoded by the human gene H6PD. The N-terminal section of H6PD belongs to the glucose-6-phosphate dehydrogenase family, while the C-terminal section belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily. H6PD is responsible primarily for the oxidation of glucose-6-phosphate and glucose. It also oxidizes other hexose-6-phosphates. H6PD catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. Reduced nicotinamide adenine dinucleotide phosphate is a necessary cofactor for the reductase activity of 11-hydroxysteroid dehydrogenase type 1, which converts hormonally inactive cortisone to active cortisol (in rodents, 11-dehydrocorticosterone to corticosterone).
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基因ID
- 9563
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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