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ANK2 抗体 (AA 1901-2100)

This anti-ANK2 antibody is a 兔 多克隆 antibody detecting ANK2 in IHC (p), ELISA, IF (cc), IF (p) 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1386782
发货至: 中国

Quick Overview for ANK2 抗体 (AA 1901-2100) (ABIN1386782)

抗原

See all ANK2 抗体
ANK2 (Ankyrin 2, Neuronal (ANK2))

适用

  • 33
  • 12
  • 12
小鼠

宿主

  • 36

克隆类型

  • 36
多克隆

标记

  • 10
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ANK2 antibody is un-conjugated

应用范围

  • 36
  • 28
  • 22
  • 10
  • 10
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    AA 1901-2100

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Ankyrin B

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ANK2 (Ankyrin 2, Neuronal (ANK2))

    别名

    Ankyrin B

    背景

    Synonyms: ANK-2, Ank2, ANK2_HUMAN, Ankyrin 2, Ankyrin 2 brain, Ankyrin B, Ankyrin nonerythroid, ANKYRIN, NEURONAL, Ankyrin-2, Ankyrin-B, Brain ankyrin, Non-erythroid ankyrin

    Background: Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain, and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin B, or brain Ankyrin is predominantly expressed in the plasma membrane of neurons as well as glial cells throughout the brain. Two transcripts have been described with alternative splicing resulting in additional isoforms. The Ankyrin B protein associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin B is required for coordinated assembly of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor at transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes.

    基因ID

    287

    途径

    Cell-Cell Junction Organization
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