KCNT2 抗体 (AA 51-150)
Quick Overview for KCNT2 抗体 (AA 51-150) (ABIN1386737)
抗原
See all KCNT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KCNT2
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亚型
- IgG
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anti-Potassium Channel, Subfamily T, Member 2 (KCNT2) (AA 1069-1097), (C-Term) antibody
KCNT2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27952 unconjugated
anti-Potassium Channel, Subfamily T, Member 2 (KCNT2) (AA 1076-1105), (C-Term) antibodyKCNT2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))
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别名
- KCNT2
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背景
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Synonyms: KCa4.2, Potassium channel, subfamily T, member 2, Sequence like an intermediate conductance potassium channel subunit, SLICK, SLO2.1, Sodium and chloride activated ATP sensitive potassium channel, Sodium and chloride activated ATP sensitive potassium channel Slo2.1, KCNT2_HUMAN.
Background: Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
抗原
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