STXBP5 抗体 (AA 235-380)
Quick Overview for STXBP5 抗体 (AA 235-380) (ABIN1386695)
抗原
See all STXBP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 235-380
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Tomosyn/STXBP5
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亚型
- IgG
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anti-Syntaxin Binding Protein 5 (Tomosyn) (STXBP5) (AA 515-610) antibody
STXBP5 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 5 (Tomosyn) (STXBP5) (AA 1031-1103) antibodySTXBP5 适用: 人, 大鼠, 小鼠, Cow WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 5 (Tomosyn) (STXBP5) (AA 1017-1115) antibodySTXBP5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- STXBP5 (Syntaxin Binding Protein 5 (Tomosyn) (STXBP5))
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别名
- Tomosyn/STXBP5
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背景
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Synonyms: FLJ30922, Lethal2 giant larvae protein homolog 3, LGL3, LLGL3, MGC141942, MGC141968, Nbla04300, STXBP5, Syntaxin binding protein 5, Syntaxin-binding protein 5, Tomosyn 1, STXB5_HUMAN.
Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Tomosyn, also known as STXBP5 (syntaxin binding protein 5), LLGL3 or LGL3, is a 1,151 amino acid protein that localizes to the cytoplasm, as well as to the cell junction, secretory vesicles and to the peripheral membrane and contains one v-SNARE coiled-coil homology domain and 14 WD repeats. Interacting with Syntaxin 1 and Syntaxin 1B, Tomosyn functions as a regulator of neurotransmitter release and calcium-dependent exocytosis. Additionally, Tomosyn inhibits membrane fusion and may play a role in the assembly of SNARE complexes between transport vesicles and the plasma membrane. Multiple isoforms of Tomosyn exist due to alternative splicing events.
抗原
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