mGluR1 + mGluR5 抗体 (AA 501-600)
Quick Overview for mGluR1 + mGluR5 抗体 (AA 501-600) (ABIN1386658)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 5/1 (mGluR1/5) (AA 651-750) antibody
mGluR1/5 适用: 小鼠, 大鼠, 人 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- mGluR1 + mGluR5 (mGluR1/5) (Glutamate Receptor, Metabotropic 5/1 (mGluR1/5))
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别名
- MGLUR1 + MGLUR5
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背景
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Synonyms: MGLUR1+MGLUR5, GPRC1A, GPRC1E, GRM1, GRM1A, GRM5, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, mGlu1, mGlu5, MGLUR1, MGLUR1A, MGLUR5, MGLUR5B, GRM1_HUMAN, GRM5_HUMAN.
Background: Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a. The Group-II receptors in include mGluR2 and mGluR3.
抗原
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