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POU3F3 抗体 (AA 351-450)

This anti-POU3F3 antibody is a 兔 多克隆 antibody detecting POU3F3 in WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN1386623
发货至: 中国

Quick Overview for POU3F3 抗体 (AA 351-450) (ABIN1386623)

抗原

See all POU3F3 抗体
POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

适用

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宿主

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克隆类型

  • 17
多克隆

标记

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This POU3F3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 351-450

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Brain1/POU3F3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

    别名

    Brain1/POU3F3

    背景

    Synonyms: Brain 1, Brain specic homeobox/POU domain protein 1, Brain-1, Brain-specic homeobox/POU domain protein 1, Brain1, BRN 1, Brn-1, BRN1, class 3, Oct-8, Octamer-binding protein 8, Octamer-binding transcription factor 8, OTF 8, OTF-8, OTF8, PO3 F3, PO3F 3, PO3F3, PO3F3_HUMAN, POU class 3 homeobox 3, POU domain, POU domain, class 3, transcription factor 3, POU3 F3, POU3F 3, Pou3f3, RHS 1, Rhs 2, RHS1, Rhs2, Skin 1, Skin1, transcription factor 3.

    Background: The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.

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