ZFPM2 抗体 (AA 701-800)
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- 抗原 See all ZFPM2 抗体
- ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))
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抗原表位
- AA 701-800
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZFPM2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FOG2
- 亚型
- IgG
- Top Product
- Discover our top product ZFPM2 Primary Antibody
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anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) antibody
ZFPM2 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (AA 982-1151) antibodyZFPM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) antibodyZFPM2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (C-Term) antibodyZFPM2 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (AA 982-1151) antibodyZFPM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) antibodyZFPM2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))
- 别名
- FOG2 (ZFPM2 产品)
- 背景
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Synonyms: FOG-2, FOG2_HUMAN, Friend of GATA 2, Friend of GATA protein 2, Friend of GATA2 , hFOG-2 , ZFPM2, Zinc finger protein 89B, Zinc finger protein M2, Zinc finger protein multitype 2 , Zinc finger protein ZFPM2.
Background: The FOG family of transcriptional cofactors, including FOG (friend of GATA-1) and FOG-2, are zinc finger proteins that interact with the GATA family of transcriptional regulators. FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, and they promote differentiation during embryonic development. These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins. While FOG cooperatively regulates GATA-1 induced transcription, FOG-2 is able to both positively and negatively influence GATA mediated transcription. FOG-2 is predominantly expressed in heart, neurons and gonads, and it preferentially participates in the regulation of GATA-3, GATA-4 and GATA-6. In cardiomyocytes and fibroblasts, FOG-2 inhibits GATA-4 transcriptional activity, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems.
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