ZFPM2 抗体 (AA 701-800)
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北京 101111
Quick Overview for ZFPM2 抗体 (AA 701-800) (ABIN1386622)
抗原
See all ZFPM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-800
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FOG2
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亚型
- IgG
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anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) antibody
ZFPM2 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (AA 982-1151) antibodyZFPM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (C-Term) antibodyZFPM2 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) antibodyZFPM2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, FOG Family Member 2 (ZFPM2) (AA 982-1151) antibodyZFPM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))
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别名
- FOG2
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背景
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Synonyms: FOG-2, FOG2_HUMAN, Friend of GATA 2, Friend of GATA protein 2, Friend of GATA2 , hFOG-2 , ZFPM2, Zinc finger protein 89B, Zinc finger protein M2, Zinc finger protein multitype 2 , Zinc finger protein ZFPM2.
Background: The FOG family of transcriptional cofactors, including FOG (friend of GATA-1) and FOG-2, are zinc finger proteins that interact with the GATA family of transcriptional regulators. FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, and they promote differentiation during embryonic development. These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins. While FOG cooperatively regulates GATA-1 induced transcription, FOG-2 is able to both positively and negatively influence GATA mediated transcription. FOG-2 is predominantly expressed in heart, neurons and gonads, and it preferentially participates in the regulation of GATA-3, GATA-4 and GATA-6. In cardiomyocytes and fibroblasts, FOG-2 inhibits GATA-4 transcriptional activity, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems.
抗原
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