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NME4 抗体 (AA 21-120)

This anti-NME4 antibody is a 兔 多克隆 antibody detecting NME4 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1386601
发货至: 中国

Quick Overview for NME4 抗体 (AA 21-120) (ABIN1386601)

抗原

See all NME4 抗体
NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This NME4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 21-120

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NME4/nm23-H4

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))

    别名

    NME4/nm23-H4

    背景

    Synonyms: mitochondrial, NDK, NDKM_HUMAN, NDP kinase, NDP kinase, mitochondrial, NDPKD, nm23 H4, nm23-H4, NM23D, Nm23M4, NME4, Non metastatic cells 4 protein expressed in, Nucleoside diphosphate kinase D, Nucleoside diphosphate kinase, mitochondrial.

    Background: The nm23 gene (Metastasis inhibition factor nm23), a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. Based on sequence analysis, nm23, also designated nucleoside diphosphate kinase A (NDK A) or Tumor metastatic process-associated protein, appears to be highly related to nucleotide diphosphate kinases (NDP). NDP kinases A and B are identical to two isotypes of human nm23 homologs, nm23-H1 and nm23-H2, respectively. nm23-H2 is also identical in sequence to PuF, a transcription factor that binds to nuclease-hypersensitive elements at positions 142 to 115 of the human c-Myc promoter. nm23-H3 and nm23-H4 are important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. nm23-H4 localizes to the mitochondrial intermembrane space and is widely expressed, with higher levels detected in prostate, heart, liver, small intestine, and skeletal muscle tissues. Low amounts of nm23-H4 are observed in the brain and in blood leukocytes.

    途径

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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