DMPK 抗体 (AA 51-120)
Quick Overview for DMPK 抗体 (AA 51-120) (ABIN1386566)
抗原
See all DMPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-120
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DMPK
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亚型
- IgG
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anti-Dystrophia Myotonica-Protein Kinase (DMPK) antibody
DMPK 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 303-420) antibodyDMPK 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 243-424) antibodyDMPK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 323-372) antibodyDMPK 适用: 人, 小鼠, Cow, 犬, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Center) antibodyDMPK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-152) antibodyDMPK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Middle Region) antibodyDMPK 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
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别名
- DMPK
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背景
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Synonyms: Dystrophia myotonica protein kinase, DM 1, DM, DM kinase, DM protein kinase, DM-kinase, DM1, DM1 protein kinase, DM1PK, DMK, DMPK, DMPK_HUMAN, Dystrophia myotonica 1, Dystrophia myotonica protein kinase, MDPK, MT PK, MT-PK, Myotonic dystrophy associated protein kinase, Myotonic dystrophy protein kinase, Myotonin protein kinase A, Myotonin protein kinase, Myotonin-protein kinase, Thymopoietin homolog.
Background: Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1). DMPK is implicated in myotonic muscular dystrophy (DM), an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2,3). DM arises through expansion of CTG repeats in the 3?-UTR of the DMPK gene (4). Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5). These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, to mediate in part the DM phenotype (6). Other substrates for DMPK include myogenin, L-type calcium channels, and Phospholemman (PLM) (1).
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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