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BCAS1 抗体 (AA 542-584)

This anti-BCAS1 antibody is a 兔 多克隆 antibody detecting BCAS1 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1386549
发货至: 中国

Quick Overview for BCAS1 抗体 (AA 542-584) (ABIN1386549)

抗原

See all BCAS1 抗体
BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 542-584

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BCAS1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Kaji, Maki, Ueda, Ishimoto, Inoue, Yasuda, Sawamura, Hikawa, Ayaki, Yamakado, Takahashi: "BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy." in: Acta neuropathologica communications, Vol. 8, Issue 1, pp. 120, (2021) (PubMed).

  • 抗原

    BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

    别名

    BCAS1/NABC1

    背景

    Synonyms: AIBC 1, AIBC1, Amplied and overexpressed in breast cancer, BCAS 1, BCAS1, BCAS1_HUMAN, Breast carcinoma amplied sequence 1, Breast carcinoma-amplied sequence 1, Novel amplied in breast cancer 1.

    Background: NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.

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