Lap1/Densin180 (AA 601-700) 抗体
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北京 101111
Quick Overview for Lap1/Densin180 (AA 601-700) 抗体 (ABIN1386526)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 601-700
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Densin180
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Lap1/Densin180
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背景
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Synonyms: Densin 180, Densin, Densin-180, densin180, DKFZp686I1147, KIAA1365, Lamin associated polypeptide 1, LAP 1, Leucine rich repeat containing 7, Leucine rich repeat containing protein 7, Leucine-rich repeat-containing protein 7,Lrrc 7, Lrrc7, LRRC7_HUMAN, MGC144918, OTTHUMP00000065336, OTTHUMP00000065337,OTTHUMP00000065338, Protein Lap 1, Protein lap1.
Background: Densin-180 is a synaptic transmembrane protein that is tightly associated with the postsynaptic density in CNS neurons and is postulated to function as a synaptic adhesion molecule. Densin-180 is a brain-specific momber of the O-sialoglycoprotein family which is highly concentrated at synapses along dendrites. The sequence of densin-180 contains 17 leucine-rich repeats, a sialomucin domain, an apparent transmembrane domain, and a PDZ (PSD-95, DIg, Z0-1) domain. The PDZ domain contributes to its binding to a-actinin. The intracellular portion of densin-180, CaMKIIa, interacts with a-actinin at distinct binding sites and, together, they form a ternary complex stabilized by multiple interactions.
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基因ID
- 57554
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UniProt
- Q96NW7
抗原
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