Fascin 3 抗体 (AA 401-498)
Quick Overview for Fascin 3 抗体 (AA 401-498) (ABIN1386492)
抗原
See all Fascin 3 (FSCN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-498
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预测反应
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Fascin-3
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Fascin 3 (FSCN3)
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别名
- FSCN3/Fascin-3
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背景
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Synonyms: Fascin testis, Fascin 3, Fascin homolog 3 actin bundling protein testicular Strongylocentrotus purpuratus , Fascin homolog 3 actin bundling protein testicular, Fascin3, FSCN 3, FSCN3, MGC94950, Testis fascin, FSCN3_HUMAN.
Background: Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.
抗原
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