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CREB3L3 抗体 (AA 201-300)

CREB3L3 适用: 人 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386470
发货至: 中国
  • 抗原 See all CREB3L3 抗体
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    抗原表位
    • 15
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 25
    • 8
    • 8
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CREB3L3 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CREB-H
    亚型
    IgG
    Top Product
    Discover our top product CREB3L3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    别名
    CREB-H/CREB3L3 (CREB3L3 产品)
    别名
    CREB-H antibody, CREBH antibody, BC010786 antibody, D10Bur1e antibody, creb3l3a antibody, creb3l3b antibody, si:dkey-110c1.2 antibody, wu:fc88h05 antibody, zgc:112279 antibody, cAMP responsive element binding protein 3 like 3 antibody, cAMP responsive element binding protein 3-like 3 antibody, cAMP responsive element binding protein 3-like 3a antibody, CREB3L3 antibody, Creb3l3 antibody, creb3l3a antibody
    背景

    Synonyms: cAMP responsive element binding protein 3 like 3, cAMP responsive element-binding protein 3 like protein 3, CREB H, CREB/ATF family transcription factor, CREBH, Cyclic AMP responsive element binding protein 3 like protein 3, cAMP-responsive element-binding protein 3-like protein 3, HYST1481, MGC126553, MGC126557, Transcription factor CREB H, CR3L3_HUMAN.

    Background: CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.

    途径
    Thyroid Hormone Synthesis
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