XPO5 抗体 (AA 221-320)
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- 抗原 See all XPO5 抗体
- XPO5 (Exportin 5 (XPO5))
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抗原表位
- AA 221-320
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XPO5 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Exportin 5
- 亚型
- IgG
- Top Product
- Discover our top product XPO5 Primary Antibody
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anti-Exportin 5 (XPO5) (AA 1-280) antibody
XPO5 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2C5-1B3 unconjugated
anti-Exportin 5 (XPO5) (AA 925-1204) antibodyXPO5 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exportin 5 (XPO5) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1115-1164) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 190-239) antibodyXPO5 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 182-231) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (N-Term) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 2-180) antibodyXPO5 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- XPO5 (Exportin 5 (XPO5))
- 别名
- Exportin 5 (XPO5 产品)
- 别名
- exp5 antibody, CG12234 antibody, Dmel\\CG12234 antibody, Exp-5 antibody, Exp5 antibody, RanBP21 antibody, dmExp5 antibody, 2410004H11Rik antibody, 2700038C24Rik antibody, AI648907 antibody, AW549301 antibody, RanBp21 antibody, mKIAA1291 antibody, exportin-5 antibody, ranbp21 antibody, DDBDRAFT_0185980 antibody, DDBDRAFT_0237583 antibody, DDB_0185980 antibody, DDB_0237583 antibody, XPO5 antibody, exportin 5 antibody, CG12234 gene product from transcript CG12234-RB antibody, armadillo-like helical domain-containing protein antibody, XPO5 antibody, Ranbp21 antibody, Xpo5 antibody, xpo5 antibody
- 背景
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Synonyms: Exp 5, Exp5, Exportin 5, Exportin-5, Exportin5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Ran binding protein 21, Ran-binding protein 21, Ranbp 21, Ranbp21, Xpo 5, xpo5, XPO5_HUMAN.
Background: Exportin 5 (XPO5) is a member of the importin _ family of proteins and functions in tRNA export in a sequence dependent fashion. More recently, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA processing occurs to produce mature miRNAs. Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells . Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired.
- 途径
- Regulatory RNA Pathways, Protein targeting to Nucleus
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