Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) 抗体
Quick Overview for Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) 抗体 (ABIN1386454)
抗原
See all Chromosome 11open Reading Frame 9 (C11orf9) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 401-500
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human MYRF
-
亚型
- IgG
-
-
anti-Chromosome 11open Reading Frame 9 (C11orf9) (AA 843-1004) antibody
C11orf9 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 11open Reading Frame 9 (C11orf9) (AA 108-157) antibodyC11orf9 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- Chromosome 11open Reading Frame 9 (C11orf9)
-
别名
- MYRF/C11orf9
-
背景
-
Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954
Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
-
基因ID
- 745
-
UniProt
- Q9Y2G1
抗原
-
